Center for Health Innovations in Reproductive and Perinatal Population Research (CHIRP)

This grant aims to utilize data from the National Health and Nutrition Survey (NHANES) linked Medicaid data to create a novel preconception cohort and study the role of preconception lifestyle factors on pregnancy outcomes. The proposed study will evaluate the role of preconception dietary factors, sleep and physical activity, and weight loss attempts and strategies on adverse pregnancy outcomes. The data obtained from this study will provide valuable insights into the role of preconception health factors improving pregnancy outcomes and can inform the development of evidence-based preconception care guidelines.  

Grant Number: R01HD114736

Principal Investigators:

Stefanie N. Hinkle, PhD

Assistant Professor of Epidemiology

Emerging ExposuresEtiology of Population HealthLife Course Epi

Ellen Caniglia, ScD

Assistant Professor of Epidemiology

Causal InferenceHealth EquityLife Course Epi

Almost half of the women of reproductive age in the U.S. are deficient in iodine. We will apply advanced novel methods to measure urinary iodine in women during preconception and throughout pregnancy and in the placenta to estimate the effects of iodine deficiency before and during pregnancy on critical reproductive and perinatal health outcomes including infertility, pregnancy loss, preterm delivery, and birth size. Iodine is a low-cost intervention, that could be used to target women at risk for adverse outcomes.

Grant Number: R01HD111643

Principal Investigator:

Stefanie N. Hinkle, PhD

Assistant Professor of Epidemiology

Emerging ExposuresEtiology of Population HealthLife Course Epi

Current U.S. guidelines recommend a daily “baby” aspirin, begun after the first trimester, to prevent preeclampsia. However, data suggest that a higher dosage of aspirin and initiating treatment immediately upon pregnancy recognition, instead of waiting until 12 weeks’ of pregnancy, may have a greater beneficial effect, while additionally protecting against pregnancy loss. We propose a randomized trial of 162 mg aspirin (equivalent to two “baby” aspirin) begun by 6 weeks’ gestation in a diverse population to evaluate its effect on preventing pregnancy loss and preeclampsia.

Grant Number: R01HD112308

Principal Investigators:

Enrique Schisterman, PhD

Chair, DBEI
Perelman Professor in Biostatistics, Epidemiology and Informatics

Causal InferenceEtiology of Population HealthNovel Methods

Kurt T. Barnhart, MD, MSCE

William Shippen, Jr. Professor of Obstetrics and Gynecology;
Professor of Epidemiology

Life Course Epi

This study will recruit at least 2,500 pregnant people, their partners, and offspring from the University of Pennsylvania and Children’s Hospital of Philadelphia as part of the nationwide ECHO Cohort to understand the role of early exposures on child health outcomes and identify ways to reduce disparities. The health system at Penn and CHOP serves a diverse population underrepresented in other pregnancy and pediatric cohorts in the US (largely Medicaid-insured and plurality Black).

Grant Number: UG3OD035537

Principal Investigators:

Sunni Mumford, PhD

Director, Epidemiology
Professor of Epidemiology

Causal InferenceClinical TrialsEmerging ExposuresHealth EquityLife Course Epi

Heather H. Burris, MD, MPH

Associate Professor of Pediatrics (Neonatology & Newborn Services) at the Children’s Hospital of Philadelphia

Sara B. Demauro, MD, MSCE

Associate Professor of Pediatrics (Neonatology & Newborn Services) at the Children’s Hospital of Philadelphia

Rates of severe maternal morbidity are rising in the U.S. and disparities in these outcomes are worsening. Telehealth utilization increased dramatically in response to the COVID-19 pandemic and has great potential to reduce severe maternal morbidity and disparities in severe maternal morbidity through increasing prenatal and postpartum care access and utilization. This community engaged mixed methods project will determine the impact of telehealth on severe maternal morbidity and disparities in severe maternal morbidity, and identify best practices for implementation of telehealth to reduce these outcomes.

Grant Number: R01HD113685

Principal Investigators:

Ellen Caniglia, ScD

Assistant Professor of Epidemiology

Causal InferenceHealth EquityLife Course Epi

Meredith Matone, DrPH, MHS

Associate Professor of Pediatrics (General Pediatrics)

Polycystic ovary syndrome is the most common endocrine disorder affecting 10% of reproductive age women and has been associated with an increased risk of heart disease. Hormonal contraceptives and metformin are first line medications, commonly prescribed from an early age and for long durations, even though how they might impact heart disease risk in women with PCOS is unknown. The goal of this project is to understand how these medications impact heart disease, and risk factors for heart disease like diabetes and high cholesterol among two large real-world cohorts of women with PCOS.

Grant Number: PCORI BPS-2022C3-30268

Principal Investigators:

Sunni Mumford, PhD

Director, Epidemiology
Professor of Epidemiology

Causal InferenceClinical TrialsEmerging ExposuresHealth EquityLife Course Epi

Anuja Dokras, MD, MHCI, PhD

Founder’s Professor in Women’s Health
Department of Obstetrics and Gynecology, Perelman School of Medicine

It can be challenging for decision makers and clinical providers when the results of randomized controlled trials conflict with each other. Currently, there are no standard methods and guidelines that can be used by decision makers in this situation, even though they are often tasked with deciding whether the treatment of interest should be available, for whom the treatment may work and whether another trial is needed. In this study, researchers will reanalyze data from two large trials of preterm birth and 17-alpha-hydroxyprogesterone caproate (17P), a weekly injection that may prevent preterm birth in individuals with a previous preterm birth. The first trial found 17P substantially reduced the risk of preterm birth, but the second confirmatory trial found there was no effect. The methods and solutions the study team develops can be applied to any pair of conflicting randomized trials. 

Grant Number: PCORI ME-2023C2-33341

Principal Investigators:

Ellen Caniglia, ScD

Assistant Professor of Epidemiology

Causal InferenceHealth EquityLife Course Epi

Enrique Schisterman, PhD

Chair, DBEI
Perelman Professor in Biostatistics, Epidemiology and Informatics

Causal InferenceEtiology of Population HealthNovel Methods

Eric Tchetgen Tchetgen, PhD

University Professor; Professor of Biostatistics; Professor of Statistics and Data Science

Causal Inference

DiTosto, J. D., Caniglia, E. C., Hinkle, S. N., Sealy, N., Schisterman, E. F., Johnstone, E., Mendola, P., Mills, J., Hotaling, J., Ryan, G., & Mumford, S. L. (2025). Target trial emulation of preconception serum vitamin D status on fertility outcomes: a couples-based approach. Fertility and Sterility, 123(2), 300-312. https://doi.org/https://doi.org/10.1016/j.fertnstert.2024.08.332

Elser, H., Mumford, S. L., Grantz, K. L., Pollack, A. Z., Mendola, P., Mills, J. L., Yeung, E., Zhang, C., Schisterman, E. F., & Hinkle, S. N. (2025). Postpartum Haemorrhage and Long‐Term Mortality. Paediatric and perinatal epidemiology., 39(3), 244-253. https://doi.org/10.1111/ppe.13166

Lee, I. T., Rees, J., King, S., Kim, A., Cherlin, T., Hinkle, S., Mumford, S. L., & Dokras, A. (2025). Depression, Anxiety, and Risk of Metabolic Syndrome in Women With Polycystic Ovary Syndrome: A Longitudinal Study. The Journal of Clinical Endocrinology & Metabolism, 110(3), e750-e756. https://doi.org/10.1210/clinem/dgae256

Matsumoto, M. M., Schisterman, E. F., Soulen, M. C., Reddy, S., Sheng, M., Khaddash, T., Damjanov, N., Furth, E. E., Hunt, S. J., Nadolski, G. J., Kaplan, D. E., & Gade, T. P. F. (2025). Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular Carcinoma: The Phase I–II Hydroxychloroquine-Transarterial Chemoembolization (qTACE) Trial. Journal of Vascular and Interventional Radiology, 36(1), 175-178. https://doi.org/10.1016/j.jvir.2024.08.012

Pineles, B. L., Bonafide, C. P., & Ashcraft, L. E. (2025). Deimplementation of ineffective and harmful medical practices: a data-driven commentary. Am J Epidemiol, 194(4), 889-897. https://doi.org/10.1093/aje/kwae285

Smith, A. J., Pancoe, S., Lynch, M. P., Wachlin, M., Powell, K., Hinkle, S. N., Koelper, N. C., Doherty, M., Bekelman, J. E., Simpkins, F., & Ko, E. M. (2025). Rideshare services for transportation assistance in gynecologic oncology: a quality improvement study. BMC Health Services Research, 25(1), 251. https://doi.org/10.1186/s12913-025-12296-6

Wagner, K. A., Chen, Z., Hinkle, S. N., Gleason, J. L., Lee, W., Grobman, W. A., Owen, J., Newman, R. B., Skupski, D. W., He, D., Sherman, S., Gore-Langton, R. E., Zhang, C., Grewal, J., & Grantz, K. L. (2025). Relationship between Gestational Weight Gain with Fetal Body Composition and Organ Volumes in the NICHD Fetal 3D Study: A Prospective Pregnancy Cohort. The American Journal of Clinical Nutrition, 121(2), 367-375. https://doi.org/10.1016/j.ajcnut.2024.12.007

Wong, J., & Margolis, D. (2025). 29: Association of Food Allergy Status with Control and Long-Term Persistence of Atopic Dermatitis: A Longitudinal Analysis of the Pediatric Eczema Elective Registry. Journal of Investigative Dermatology, 145(3), e8. https://doi.org/10.1016/j.jid.2025.02.040

Caniglia EC, Zash R, Diseko M, Mabuta J, Mmalane M, Lockman S, Mayondi G, Masheto G, Makhema J, Shapiro R. Target trials of pre-conception switch from Nevirapine- or Efavirenz-based ART to dolutegravir-based ART on adverse birth and maternal outcomes. AIDS. 2025 Aug 13. doi: 10.1097/QAD.0000000000004321. Epub ahead of print. PMID: 40811078

Virkud AV, Tchetgen ET, Schisterman EF, Pineles B, Levine LD, Cole SR, Hinkle SN, Mumford S, Gerson KD, Taylor BD, Blackwell S, Peaceman A, Parry S, Johnson MT, Willis D, Caniglia EC. Clarifying Contradictions: Transportability in 17OHP-C Trials and Preterm Birth Outcomes Using Doubly Debiased Machine Learning. Am J Epidemiol. 2025 Sep 24:kwaf202. doi: 10.1093/aje/kwaf202. Epub ahead of print. PMID: 40990932

Smith ER, Gomes F, Adu-Afarwuah S, Aguayo VM, El Arifeen S, Bhutta ZA, Caniglia EC, Christian P, Devakumar D, Dewey KG, Fawzi WW, Friis H, Gomo E, Guindo O, Hallamaa L, Isanaka S, Kæstel P, Lachat C, Maleta K, Moore SE, Oakley EM, Osrin D, Rahman A, Rana Z, Rizvi A, Roberfroid D, Shaikh S, Sonko B, Soofi SB, Subarkah I, Sunawang R, Wang D, West KP Jr, Wu LSF, Zagre N, Bourassa MW, Sudfeld CR. Contribution of Maternal Adherence to the Effect of Multiple Micronutrient Supplementation During Pregnancy: A Systematic Review and Individual Participant Data Meta-analysis. Adv Nutr. 2025 Jul;16(7):100455. doi: 10.1016/j.advnut.2025.100455. Epub 2025 May 30. PMID: 40451462; PMCID: PMC12268027.

DiTosto JD, Sealy NRZ, Hinkle SN, Schisterman EF, Dokras A, Mumford SL, Caniglia EC. The Invisible Burden: Examining the Impact of Exposure Misclassification in Epidemiologic Analyses of Uterine Fibroids. Paediatr Perinat Epidemiol. 2025 Jul 7. doi: 10.1111/ppe.70027. Epub ahead of print. PMID: 40622743.

Dib BN, Caniglia EC, Brummel S, Shapiro R, Swanson SA. Selection Biases in Perinatal Research: A Comparison of Inverse Probability Weighting, Instrumental Variable and Sibling-Comparison Design. Paediatr Perinat Epidemiol. 2025 Apr 25:10.1111/ppe.70021. doi: 10.1111/ppe.70021. Epub ahead of print. PMID: 40276874; PMCID: PMC12353985.

Manandhar-Sasaki P, Ban KF, Richard E, Braithwaite RS, Caniglia EC: How likely isunmeasured confounding to explain meta-analysis-derived associations between alcohol, other substances, and mood-related conditions with HIV risk behaviors? BMC Med Res Methodol 25(1): 62, Mar 2025 Notes: doi: 10.1186/s12874-025-02490-9.

Dryden-Peterson S, Kim A, Caniglia EC, Joyce M, Rubins D, Kim AY, Fangman J, Baden LR, Wooley AE: Severe outcomes of COVID-19 among adults with increased risk conditions: A population-based observational study PLoS One 20(2): e0316529, Feb 2025 Notes: doi: 10.1371/journal.pone.031652

DiTosto J, Caniglia EC, Hinkle SN, Sealy N, Schisterman EF, Johnstone E, Mendola P, Mills J, Hotaling J, Ryan G, Mumford SL: Target trial emulation of preconception serum vitamin D status on fertility outcomes: a couples-based approach Fertility and Sterility 123(2): 300-312, Feb 2025.

Caniglia EC, Zash R, Diseko M, Mayondi G, Mabuta J, Mmalane M, Makhema J, Jacobson DL, Bengtson AM, Lockman S, Shapiro R, Swanson SA. : How much could anemia-related interventions reduce the HIV disparity in adverse birth outcomes? American Journal of Epidemiology 194(1): 122-131, January 2025.

DiTosto JD, Zash R, Jacobson DL, Johnson K, Diseko M, Mayondi G, Mabuta J, Mmalane M, Makhema J, Mumford SL, Lockman S, Shapiro R, Caniglia EC. Safety of Antihypertensive Medication for the Management of Non-Severe Gestational Hypertension Among Pregnant Individuals in Botswana-Emulating a Series of Target Trials. Paediatr Perinat Epidemiol. 2025 Oct 21. doi: 10.1111/ppe.70079. Epub ahead of print. PMID: 41121542.

Latour CD, Klose M, Edwards JK, Song Z, Jonsson Funk M, Wood ME. Healthy Live Births as Censoring Versus Competing Events in Studies of Prenatal Medication Use. Paediatric and Perinatal Epidemiology. 2025. 0:1-11. doi: 10.1111/ppe.70043. PMID: 40620149

Thel H, Latour CD, Tsevat D, Dissanayake MV, Wood ME, Arora KS. Prevalence of Permanent Contraception and Long-Acting Reversible Contraceptives Among a Commercially – Insured US Population, 2010-2022. American Journal of Obstetrics & Gynecology. 2025. 233(2):E50-E52. doi: 10.1016/j.ajog.2025.04.023. PMID: 40254277

Meng LC, Chuang HM, Lai HY, Chen HM, Yang KY, Chen LK, Hsiao FY. Frailty-stratified effectiveness of SGLT2 inhibitors versus DPP-4 inhibitors and GLP-1 receptor agonists on pulmonary outcomes in type 2 diabetes: a nationwide cohort study. EClinicalMedicine. 2025 Jul 3;85:103332

Hsiao FY, Li YH, Lai HY, Meng LC, Chuang HM, Chen HM, Shih CL, Chen WJ. Clinical burden and management gaps in atherosclerotic cardiovascular disease: A nationwide study of 687,212 patients in Taiwan, 2017-2023. IJC Heart & Vasculature. 2025 Jul 16;60:101749.

Chuang HM, Meng LC, Lin CW, Chen WW, Chen YY, Shang CY, Chen LK, Hsiao FY. Unveiling the hidden triad of antidepressants, benzodiazepines, and Z-hypnotics during pregnancy: A 15-year population-based study in Taiwan. Journal of Affective Disorders. 2025 Sep 15;385:119372.

Huang ST, Otsuka R, Nishita Y, Meng LC, Hsiao FY, Shimokata H, Chen LK, Arai H. Risk of Sarcopenia Following Long-Term Statin Use in Community-Dwelling Middle-Aged and Older Adults in Japan. The Journal of Cachexia, Sarcopenia and Muscle. 2025;16(1):e13660.

Olivas-Martinez A, Gao F, Janes H. A General Framework for Designing and Evaluating Active-Controlled Trials with Non-Inferiority Objectives. arXiv preprint arXiv: 2510.22071. 2025 Oct 24.

Carone M, Wolock CJ, Olivas-Martinez A, Rotnitzky A, Gilbert PB. Immune Correlates and Vaccine Immunobridging: Statistical Innovations, Challenges, and Opportunities. The Journal of Infectious Diseases. 2025 Sep 16. Online ahead of print. doi: 10.1093/infdis/jiaf451

Olivas-Martinez A, Rotnitzky A. Source-Condition Analysis of Kernel Adversarial Estimators. arXiv preprint arXiv:2508.17181. 2025 Aug 24.

Zhao Y, Gulati R, Lange J, Olivas-Martinez A, Raoof S, Zheng Y, Feng Z, Etzioni R. Sensitivity Measures in Studies of Cancer Early Detection Biomarkers. Cancer Epidemiology, Biomarkers & Prevention. 2025 Jun 3;34(6):944-51. doi.org/10.1158/1055-9965.EPI-24-1849

DiTosto JD, Zash R, Jacobson DL, Johnson K, Diseko M, Mayondi G, Mabuta J, Mmalane M, Makhema J, Mumford SL, Lockman S, Shapiro R, Caniglia EC. Safety of Antihypertensive Medication for the Management of Non-Severe Gestational Hypertension Among Pregnant Individuals in Botswana-Emulating a Series of Target Trials. Paediatr Perinat Epidemiol. 2025 Oct 21. doi: 10.1111/ppe.70079. Epub ahead of print. PMID: 41121542.

Doss GL, Daniels JL, Mumford SL, Poole C, Steiner AZ, Schisterman EF, Silver RM, Klawans MR, Jukic AMZ. Pregnancy Length Measurement Error: A comparison of Last Menstrual Period and Ultrasonography with Ovulation-Based Estimation. Epidemiology. 2025 Sep 19. doi: 10.1097/EDE.0000000000001918. Epub ahead of print. PMID: 40981999.

Russo LM, Pilsner JR, Canty TP, Perkins NJ, Mendola P, Schliep K, Shaaban M, Hemmert RB, Singh A, Ring AM, Peterson CM, Rabeya K, Schisterman EF, Mumford SL, Nobles C. Ambient air pollution during developmental windows of spermatogenesis and semen quality among an infertility treatment seeking population. Ecotoxicol Environ Saf. 2025 Sep 15;303:118955. doi: 10.1016/j.ecoenv.2025.118955. Epub 2025 Aug 30. PMID: 40886599; PMCID: PMC12413662.

Lee IT, Barnhart KT, Hwang WT, Hinkle SN, Johnstone E, Mills JL, Caniglia EC, Schisterman EF, Mendola P, Ryan GL, Hotaling J, Peterson CM, Van Voorhis BJ, Mumford SL. Association between markers of female adiposity and live birth among patients undergoing fertility treatment or attempting unassisted conception. Hum Reprod. 2025 Sep 1;40(9):1671-1680. doi: 10.1093/humrep/deaf124. PMID: 40605077.

Hinkle SN, Okeh CC, Ulloa-Pérez E, Mani A, Higginbotham EJ, Thomas R, Kearney MD, Fahl C, Schisterman EF, Verma SS, Hamilton R, Mumford SL. Perceptions of Institutional Engagement and Inclusion by Sexual Orientation and Gender Identity. JAMA Netw Open. 2025 Jun 2;8(6):e2513772. doi: 10.1001/jamanetworkopen.2025.13772. PMID: 40465293; PMCID: PMC12138678.

Freeman JR, Whitcomb BW, Bertone-Johnson ER, O’Brien LM, Dunietz GL, Purdue-Smithe AC, Kim K, Silver RM, Schisterman EF, Mumford SL. Preconception sleep, pregnancy loss, and adverse pregnancy outcomes among women with a history of pregnancy loss. Hum Reprod. 2025 Jul 1;40(7):1366-1376. doi: 10.1093/humrep/deaf074. PMID: 40267399; PMCID: PMC12222616.

Freeman JR, Whitcomb BW, Bertone-Johnson ER, O’Brien LM, Dunietz GL, Purdue-Smithe AC, Kim K, Silver RM, Schisterman EF, Mumford SL. Sleep characteristics in association with risk of sporadic anovulation among eumenorrheic women. Chronobiol Int. 2025 Apr;42(4):500-510. doi: 10.1080/07420528.2025.2481165. Epub 2025 Mar 31. PMID: 40162646.

Abernathy A, Goba M, Forkpa M, Chittams J, Mumford SL, Srinivas SK, Schreiber CA. Inequitable Screening for Pregnancy Intention by Race, Insurance, and Site of Care in Two High-Volume Urban Obstetric Hospitals. J Womens Health (Larchmt). 2025 Apr;34(4):469-475. doi: 10.1089/jwh.2024.0859. Epub 2025 Feb 11. PMID: 39932801; PMCID: PMC12372913.

Marques IF, Domènech-Panicello C, Geurtsen ML, Hoang TT, Richmond R, Polinski K, Sirignano L, Page CM, Binter AC, Everson T, Burt A, Deuschle M, Gilles M, Streit F, Mumford SL, Magnus P, Reiss IKM, Vermeulen MJ, Witt SH, Chaves I, Yeung E, London SJ, Guxens M, Felix JF. Associations of maternal night shift work during pregnancy with DNA methylation in offspring: a meta-analysis in the PACE consortium. Clin Epigenetics. 2025 Jan 22;17(1):12. doi: 10.1186/s13148-024-01810-y. PMID: 39844285; PMCID: PMC11756212.

Chakraborti Y, Hinkle SN, Jensen JS, Haggerty CL, Darville T, Mumford SL, Schisterman EF, Silver RM, Taylor BD. Preconception Chlamydia trachomatis seropositivity and fecundability, live birth, and adverse pregnancy outcomes. Fertil Steril. 2025 Jun;123(6):1072-1081. doi: 10.1016/j.fertnstert.2024.12.017. Epub 2024 Dec 18. PMID: 39701359; PMCID: PMC12158647.

Wang S, Casey E, Sordillo J, Aguilar-Lacasaña S, Morales Berstein F, Biedrzycki RJ, Brescianini S, Chen S, Hough A, Isaevska E, Kim WJ, Lecorguillé M, Li SS, Page CM, Park J, Röder S, Salontaji K, Santorelli G, Sun Y, Won S, Zillich E, Zillich L, Annesi-Maesano I, Arshad SH, Bustamante M, Cecil CAM, Elliott HR, Ewart S, Felix JF, Gagliardi L, Håberg SE, Herberth G, Heude B, Holloway JW, Huels A, Karmaus W, Koppelman GH, London SJ, Mumford SL, Nisticò L, Popovic M, Rusconi F, Schisterman EF, Stein DJ, Send T, Tiemeier H, Vonk JM, Vrijheid M, Wiemels JL, Witt SH, Wright J, Yeung EH, Zar HJ, Zenclussen AC, Zhang H, Chavarro JE, Hivert MF. Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium. Sci Adv. 2024 Nov 29;10(48):eadr2084. doi: 10.1126/sciadv.adr2084. Epub 2024 Nov 27. PMID: 39602535; PMCID: PMC11601205.

Lee IT, Wu J, Koelper N, Mumford SL, Barnhart KT, Roe AH. Prediction of menstrual cycle phase using cross-sectional measurements of reproductive hormones. Fertil Steril. 2025 Mar;123(3):532-533. doi: 10.1016/j.fertnstert.2024.10.015. Epub 2024 Oct 18. PMID: 39426701.

DiTosto JD, Caniglia EC, Hinkle SN, Sealy N, Schisterman EF, Johnstone E, Mendola P, Mills J, Hotaling J, Ryan G, Mumford SL. Target trial emulation of preconception serum vitamin D status on fertility outcomes: a couples-based approach. Fertil Steril. 2025 Feb;123(2):300-312. doi: 10.1016/j.fertnstert.2024.08.332. Epub 2024 Aug 20. PMID: 39173703; PMCID: PMC11788044.

Lee IT, Rees J, King S, Kim A, Cherlin T, Hinkle S, Mumford SL, Dokras A. Depression, Anxiety, and Risk of Metabolic Syndrome in Women With Polycystic Ovary Syndrome: A Longitudinal Study. J Clin Endocrinol Metab. 2025 Feb 18;110(3):e750-e756. doi: 10.1210/clinem/dgae256. PMID: 38609160.

Dunietz GL, Shedden K, Lyu X, Chervin RD, Baylin A, O’Brien LM, Jansen EC, Wactawski-Wende J, Schisterman EF, Mumford SL. Patterns of Sleep Duration and Metabolic Biomarkers Across the Menstrual Cycle. J Clin Endocrinol Metab. 2025 Jan 21;110(2):e363-e371. doi: 10.1210/clinem/dgae191. PMID: 38529946; PMCID: PMC11747681.

Wolk CB, O’Brien CS, Bonafide C, Beidas RS, Schisterman EF, Albanowski K, Brent C, Schondelmeyer AC. Caregiver experiences with deimplementation of continuous pulse oximetry monitoring for children hospitalized with bronchiolitis: A qualitative study. J Hosp Med. 2025 Jul 3:10.1002/jhm.70123. doi: 10.1002/jhm.70123. Epub ahead of print. PMID: 40611404; PMCID: PMC12240481.

Schwarze JE, Tennant PWG, Barnhart K, Platt RW, Gupta S, Venetis C, D’Hooghe T, Schisterman EF. Recommendation to improve the rigor and impact of nonrandomized studies of interventions in fertility treatment research. Fertil Steril. 2025 Oct;124(4):749-758. doi: 10.1016/j.fertnstert.2025.05.168. Epub 2025 Jun 2. PMID: 40467028.

Daniel S, Dean LT, Lesko CR, Telljohann H, Biddle LE, Schisterman EF, Editorial Board OBOT. What Happens to Your Manuscript: Characteristics of Papers Published in Volume 193 of the American Journal of Epidemiology. Am J Epidemiol. 2025 May 8:kwaf104. doi: 10.1093/aje/kwaf104. Epub ahead of print. PMID: 40354826.

Schisterman EF, Lesko C, Dean LT, Jackson J. Rethinking manuscript categories to reflect the future of Epidemiology. Am J Epidemiol. 2025 Aug 5;194(8):2128-2130. doi: 10.1093/aje/kwaf099. PMID: 40331759.

Elser H, Mumford SL, Grantz KL, Pollack AZ, Mendola P, Mills JL, Yeung E, Zhang C, Schisterman EF, Hinkle SN. Postpartum Haemorrhage and Long-Term Mortality. Paediatr Perinat Epidemiol. 2025 Mar;39(3):244-253. doi: 10.1111/ppe.13166. Epub 2025 Feb 25. PMID: 40007204; PMCID: PMC11996604.

Puvvula J, Hwang WT, McCandless L, Xie C, Braun JM, Vuong AM, Oulhote Y, Schisterman EF, Shinohara RT, Booij L, Bouchard MF, Linn K, Borghese MM, Seguin JR, Zidek A, Till C, Fraser W, Yolton K, Cecil KM, Ashley-Martin J, Arbuckle TE, Lanphear B, Chen A. Gestational exposure to environmental chemical mixtures and cognitive abilities in children: A pooled analysis of two North American birth cohorts. Environ Int. 2025 Feb;196:109298. doi: 10.1016/j.envint.2025.109298. Epub 2025 Jan 29. PMID: 39893913; PMCID: PMC11896093.

Matsumoto MM, Schisterman EF, Soulen MC, Reddy S, Sheng M, Khaddash T, Damjanov N, Furth EE, Hunt SJ, Nadolski GJ, Kaplan DE, Gade TPF. Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular Carcinoma: The Phase I-II Hydroxychloroquine-Transarterial Chemoembolization (qTACE) Trial. J Vasc Interv Radiol. 2025 Jan;36(1):175-178. doi: 10.1016/j.jvir.2024.08.012. Epub 2024 Aug 23. PMID: 39181530.

Kinsey EW, Caceres OM, Posner HEK, Hinkle SN. Food insecurity during pregnancy and associated perinatal outcomes: a scoping review. Epidemiol Rev. 2025 Jan 10;47(1):mxaf001. doi: 10.1093/epirev/mxaf001. PMID: 39968733; PMCID: PMC11891647.

Smith AJ, Pancoe S, Lynch MP, Wachlin M, Powell K, Hinkle SN, Koelper NC, Doherty M, Bekelman JE, Simpkins F, Ko EM. Rideshare services for transportation assistance in gynecologic oncology: a quality improvement study. BMC Health Serv Res. 2025 Feb 14;25(1):251. doi: 10.1186/s12913-025-12296-6. PMID: 39953484; PMCID: PMC11829427.

Wagner KA, Chen Z, Hinkle SN, Gleason JL, Lee W, Grobman WA, Owen J, Newman RB, Skupski DW, He D, Sherman S, Gore-Langton RE, Zhang C, Grewal J, Grantz KL. Relationship between gestational weight gain with fetal body composition and organ volumes in the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Fetal Dimensional Study: a prospective pregnancy cohort. Am J Clin Nutr. 2025 Feb;121(2):367-375. doi: 10.1016/j.ajcnut.2024.12.007. Epub 2025 Jan 16. PMID: 39909708; PMCID: PMC11863319.

Pineles BL, Jain R, Kazmerski TM, Taylor-Cousar JL, Chambers C, Foil KL, Roe AH, Szentpetery SE. Pregnancy in Patients With Cystic Fibrosis. Obstet Gynecol. 2025 Oct 2. doi: 10.1097/AOG.0000000000006084. Epub ahead of print. PMID: 41037817.

Pineles BL, Bonafide CP, Ashcraft LE. Deimplementation of ineffective and harmful medical practices: a data-driven commentary. Am J Epidemiol. 2025 Apr 8;194(4):889-897. doi: 10.1093/aje/kwae285. PMID: 39142696.

Gurka KK, Burris HH, Ciciolla L, Coles CD, Massey SH, Newman S, Rajagopalan V, Smith LM, Zilverstand A, Bandoli G; HBCD Pregnancy Exposures, Including Substances Workgroup. Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach. Dev Cogn Neurosci. 2025 Jan;71:101494. doi: 10.1016/j.dcn.2024.101494. Epub 2024 Dec 14. PMID: 40455057; PMCID: PMC11743802.

White LK, Perlstein S, Gorgone A, Himes MM, Kornfield SL, Shanmugan S, Weitz E, Njoroge WFM, Duncan AF, Burris HH, Laney N, Gur RE, Waller RE, Chaiyachati BH. Evidence for missed cases of postpartum depression based on paediatric clinical care screenings. Br J Psychiatry. 2025 Jun;226(6):421-423. doi: 10.1192/bjp.2025.81. PMID: 40545256; PMCID: PMC12352118.

Parnes MF, Mosley L, Burris HH, Weiss EM. Climate change and environmental degradation: bioethical considerations and impact for neonatal care. Semin Perinatol. 2025 Oct;49(6):152099. doi: 10.1016/j.semperi.2025.152099. Epub 2025 Jun 12. PMID: 40514319.

Mari KE, Hoke MK, Darden N, Burris HH. Associations of NICU-Specific Stressors with Postpartum Depression in a Freestanding Children’s Hospital NICU. Am J Perinatol. 2025 Jul 24. doi: 10.1055/a-2655-3870. Epub ahead of print. PMID: 40719079.

Remigio RV, Burris HH, Clougherty JE. Exposure to violence and socioeconomic deprivation in susceptibility to nitrogen dioxide on term infant birthweight in New York City. Environ Health. 2025 May 31;24(1):33. doi: 10.1186/s12940-025-01189-0. PMID: 40450324; PMCID: PMC12125727.

Dolin CD, Burris HH. Looking Beyond the Individual: The Impact of Neighbourhood on Gestational Diabetes. Paediatr Perinat Epidemiol. 2025 May;39(4):346-347. doi: 10.1111/ppe.70009. PMID: 40439271; PMCID: PMC12121329.

Waller R, Kornfield SL, White LK, Chaiyachati BH, Barzilay R, Njoroge W, Parish-Morris J, Duncan AF, Himes MM, Rodriguez Y, Seidlitz J, Riis V, Burris HH, Gur RE, Elovitz MA. Correction to: Clinician-reported childbirth outcomes, patient-reported childbirth trauma, and risk for postpartum depression. Arch Womens Ment Health. 2025 Oct;28(5):1355. doi: 10.1007/s00737-025-01595-w. Erratum for: Arch Womens Ment Health. 2022 Oct;25(5):985-993. doi: 10.1007/s00737-022-01263-3. PMID: 40387906.

Burris HH, Darden N, Power M, Walker L, Ledyard R, Reiter J, Lewey J, Trout KK, Tan M, Gregory EF, DeMauro SB, Lorch SA, Christ L, Handley SC, Montoya-Williams D, Durnwald C. Postpartum care in the neonatal intensive care unit, PeliCaN: a randomized controlled trial. Am J Obstet Gynecol MFM. 2025 Jul;7(7):101689. doi: 10.1016/j.ajogmf.2025.101689. Epub 2025 Jun 16. PMID: 40334984; PMCID: PMC12213141.

Nelin T, Radack JK, DeMauro SB, Goldstein Novick NP, Scott K, Just AC, Burris HH. Modelling the association of reduction in PM2.5 with medically attended acute respiratory illness in infants with mild bronchopulmonary dysplasia. Arch Dis Child Fetal Neonatal Ed. 2025 Aug 19;110(5):521-522. doi: 10.1136/archdischild-2025-328533. PMID: 40274379; PMCID: PMC12353573.

Burris HH, Salazar EG. Factors associated with teenage preterm birth in the USA, a call for structural interventions. Arch Dis Child. 2025 Aug 18;110(9):671-672. doi: 10.1136/archdischild-2024-328437. PMID: 40210452.

Scott K, Ledyard RF, Darden N, Durnwald C, Handley SC, Nelin TD, Power M, Sinclair TR, Burris HH. Postpartum care receipt among parents of preterm infants admitted to the neonatal intensive care unit. Am J Obstet Gynecol MFM. 2025 May;7(5):101659. doi: 10.1016/j.ajogmf.2025.101659. Epub 2025 Mar 1. PMID: 40032179; PMCID: PMC12165275.

Mullin AM, Fleisch AF, Mesaros C, Ledyard R, Hacker MR, Burris HH. Perfluoroalkyl substances and preterm birth. J Perinatol. 2025 Apr;45(4):539-541. doi: 10.1038/s41372-025-02231-2. Epub 2025 Feb 18. PMID: 39966676; PMCID: PMC12087794.

Burris HH, White LK, Waller R, Chaiyachati BH. Oxytocin receptor epigenetics: from biomarker to potential therapeutic target. Pediatr Res. 2025 Mar;97(4):1255-1257. doi: 10.1038/s41390-024-03686-3. Epub 2024 Nov 7. PMID: 39511439.

Holloway KR, Radack J, Barreto A, Chaiyachati BH, Montoya-Williams D, Ellison AM, Burris HH. The “Other” race category on birth certificates and its impact on analyses of preterm birth inequity. J Perinatol. 2025 Mar;45(3):372-377. doi: 10.1038/s41372-024-02123-x. Epub 2024 Sep 20. PMID: 39304729; PMCID: PMC11890957.

Murosko DC, Radack J, Barreto A, Passarella M, Formanowski B, McGann C, Nelin T, Paul K, Peña MM, Salazar EG, Burris HH, Handley SC, Montoya-Williams D, Lorch SA. County-Level Structural Vulnerabilities in Maternal Health and Geographic Variation in Infant Mortality. J Pediatr. 2025 Jan;276:114274. doi: 10.1016/j.jpeds.2024.114274. Epub 2024 Aug 30. PMID: 39216622; PMCID: PMC11645216.

White LK, Himes MM, Waller R, Njoroge WFM, Chaiyachati BH, Barzilay R, Kornfield SL, Burris HH, Seidlitz J, Parish-Morris J, Brady RG, Gerstein ED, Laney N, Gur RE, Duncan AF. The Influence of Pandemic-Related Worries During Pregnancy on Child Development at 12 Months. Child Psychiatry Hum Dev. 2025 Aug;56(4):923-937. doi: 10.1007/s10578-023-01605-x. Epub 2023 Oct 8. PMID: 37805964; PMCID: PMC10999505.

Albanowski, K., Brent, C., Landrigan, C. P., Benjamin Wolk, C., Schondelmeyer, A. C., Brady, P. W., Beidas, R. S., Schisterman, E. F., Bonafide, C. P., & Network, P. R. i. I. S. (2024). Getting Started With Multi-site Research: Lessons From the Eliminating Monitor Overuse (EMO) Study. Hospital Pediatrics, 14(3), e181-e188. https://doi.org/10.1542/hpeds.2023-007550

Azria, E., Haaser, T., Schmitz, T., Froeliger, A., Bouchghoul, H., Madar, H., Pineles, B. L., & Sentilhes, L. (2024). The ethics of induction of labor at 39 weeks in low-risk nulliparas in research and clinical practice. American Journal of Obstetrics and Gynecology, 230(3, Supplement), S775-S782. https://doi.org/https://doi.org/10.1016/j.ajog.2023.07.037

Bartal, M., Blackwell, S., Zvavanjanja, R., Papanna, R., Sibai, B., Pineles, B., Coselli, J., & Ghorayeb, T. (2024). Leaving the Placenta In Situ in Placenta Accreta Spectrum Disorders: A Single-Center Case Series. American Journal of Perinatology, 41, e420–e429. https://doi.org/10.1055/a-1885-1942

Bouchghoul, H., Madar, H., Resch, B., Pineles, B. L., Mattuizzi, A., Froeliger, A., & Sentilhes, L. (2024). Uterine-sparing surgical procedures to control postpartum hemorrhage. American Journal of Obstetrics & Gynecology, 230(3), S1066-S1075.e1064. https://doi.org/10.1016/j.ajog.2022.06.018

Chakraborti, Y., Hinkle, S. N., Jensen, J. S., Haggerty, C. L., Darville, T., Mumford, S. L., Schisterman, E. F., Silver, R. M., & Taylor, B. D. Preconception Chlamydia trachomatis seropositivity and fecundability, live birth, and adverse pregnancy outcomes. Fertility and Sterility. https://doi.org/10.1016/j.fertnstert.2024.12.017

Francis, E. C., Hunt, K. J., Grobman, W. A., Skupski, D. W., Mani, A., & Hinkle, S. N. (2024). Maternal Obesity and Differences in Child Urine Metabolome. Metabolites, 14(11), 574. https://www.mdpi.com/2218-1989/14/11/574

Fuxench, Z. C. C., Mitra, N., Wong, J., Hoffstad, O., Hinkle, S., & Margolis, D. J. (2024). Maternal history of angioma is associated with infantile hemangioma and port-wine stain in children: a population-based, cohort study of mother-child pairs from the United Kingdom. Archives of Dermatological Research, 316(8), 506. https://doi.org/10.1007/s00403-024-03247-y

Joseph, K. S., Lisonkova, S., Boutin, A., Muraca, G. M., Razaz, N., John, S., Sabr, Y., Chan, W.-S., Mehrabadi, A., Brandt, J. S., Schisterman, E. F., & Ananth, C. V. (2024). Maternal mortality in the United States: are the high and rising rates due to changes in obstetrical factors, maternal medical conditions, or maternal mortality surveillance? American Journal of Obstetrics & Gynecology, 230(4), 440.e441-440.e413. https://doi.org/10.1016/j.ajog.2023.12.038

Joseph, K. S., Lisonkova, S., Boutin, A., Muraca, G. M., Razaz, N., John, S., Sabr, Y., Chan, W.-S., Mehrabadi, A., Brandt, J. S., Schisterman, E. F., & Ananth, C. V. (2024). Why improved surveillance is critical for reducing maternal deaths in the United States: a response to the American College of Obstetricians and Gynecologists. American Journal of Obstetrics & Gynecology, 231(2), e87-e92. https://doi.org/10.1016/j.ajog.2024.05.003

Joseph, K. S., Lisonkova, S., Boutin, A., Muraca, G. M., Razaz, N., John, S., Sabr, Y., Simon, S., Kögl, J., Suarez, E. A., Chan, W.-S., Mehrabadi, A., Brandt, J. S., Schisterman, E. F., & Ananth, C. V. (2024). Spatiotemporal patterns and surveillance artifacts in maternal mortality in the United States: a population-based study. The Lancet Regional Health – Americas, 39, 100902. https://doi.org/https://doi.org/10.1016/j.lana.2024.100902

Joseph, K. S., Lisonkova, S., John, S., Sabr, Y., Boutin, A., Muraca, G. M., Razaz, N., Chan, W.-S., Mehrabadi, A., Brandt, J. S., Schisterman, E. F., & Ananth, C. V. (2024). Temporal changes in maternal mortality in the United States. American Journal of Obstetrics & Gynecology, 231(2), e96-e98. https://doi.org/10.1016/j.ajog.2024.04.056

McCaffrey, D. F., Griffin, B. A., Robbins, M., Chakraborti, Y., Coffman, D. L., & Vegetabile, B. (2024). Estimating generalized propensity scores with survey and attrition weighted data. Statistics in Medicine, 43(11), 2183-2202. https://doi.org/https://doi.org/10.1002/sim.10039

Mitro, S. D., Sundaram, R., Grandi, S. M., Hinkle, S. N., Mills, J. L., Mendola, P., Mumford, S. L., Qiao, Y., Cifuentes, A., Zhang, C., Schisterman, E. F., & Grantz, K. L. (2024). Cesarean delivery, labor duration, and mothers’ mortality risk over 50 years of follow-up. American Journal of Obstetrics & Gynecology MFM, 6(11), 101498. https://doi.org/https://doi.org/10.1016/j.ajogmf.2024.101498

Mitro, S. D., Sundaram, R., Qiao, Y., Gleason, J. L., Yeung, E., Hinkle, S. N., Mendola, P., Mills, J. L., Grandi, S. M., Mumford, S. L., Schisterman, E. F., Zhang, C., & Grantz, K. L. (2024). History of multifetal gestation and long-term maternal mortality. Paediatric and Perinatal Epidemiology, 38(3), 219-226. https://doi.org/https://doi.org/10.1111/ppe.13020

Na, M., Shetty, S. S., Niu, X., Hinkle, S. N., Zhang, C., & Gao, X. (2024). Sleep duration, napping behaviors and restless legs syndrome during pregnancy and the trajectories of ultrasonographic measures of fetal growth: Findings from the NICHD Fetal Growth Studies–Singletons. Sleep Health, 10(4), 462-469. https://doi.org/https://doi.org/10.1016/j.sleh.2024.04.004

Pineles, B. L., Vial, M., Castro, T., Ghorayeb, T., Ajishegiri, O., Sadek, S., Pedroza, C., Blackwell, S. C., Chauhan, S. P., & Sibai, B. M. (2024). Ambulation for latency during expectant management of preterm prelabor rupture of membranes: a randomized controlled trial (AMBLE). American Journal of Obstetrics & Gynecology MFM, 6(1), 101218. https://doi.org/https://doi.org/10.1016/j.ajogmf.2023.101218

Shaaban, M., Shepelak, Z. D., Stanford, J. B., Silver, R. M., Mumford, S. L., Schisterman, E. F., Hinkle, S. N., Nkoy, F. L., Theilen, L., Page, J., Woo, J. G., Brown, B. H., Varner, M. W., & Schliep, K. C. (2024). Low-dose aspirin, maternal cardiometabolic health, and offspring respiratory health 9 to 14 years after delivery: Findings from the EAGeR Follow-up Study. Paediatric and Perinatal Epidemiology, 38(7), 570-580. https://doi.org/https://doi.org/10.1111/ppe.13097

Wagner, K. A., Gleason, J. L., Chen, Z., Zhang, C., Hinkle, S. N., He, D., Lee, W., Newman, R. B., Owen, J., Skupski, D. W., Grobman, W. A., Sherman, S., Tekola-Ayele, F., Grewal, J., & Grantz, K. L. (2024). Maternal Glycemic Status and Longitudinal Fetal Body Composition and Organ Volumes Based on Three-Dimensional Ultrasonography. Diabetes Care, 47(12), 2180-2188. https://doi.org/10.2337/dc24-1068

Yisahak, S. F., Hinkle, S. N., Mumford, S. L., Grantz, K. L., Zhang, C., Newman, R. B., Grobman, W. A., Albert, P. S., Sciscione, A., Wing, D. A., Owen, J., Chien, E. K., Buck Louis, G. M., & Grewal, J. (2024). Nutritional Intake in Dichorionic Twin Pregnancies: A Descriptive Analysis of a Multisite United States Cohort. Maternal and Child Health Journal, 28(2), 206-213. https://doi.org/10.1007/s10995-023-03802-5