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Target Trial Emulation & Real-World Evidence: A Practical Short Course

Virtual Workshop from June 9–12 and June 15–18, 2026

Synchronous, practical online short course focused on trial emulation and real-world evidence (RWE). The program integrates lectures, hands-on computer labs, and discussion-based journal clubs, enabling participants to learn and apply core concepts such as target trial emulation, bias and confounding control, and the use of external comparator groups, with the opportunity to earn a certificate of completion from a globally recognized academic center.

Charles E. Leonard, PharmD, MSCE, MPH, FISPE
Associate Professor of Epidemiology

Hosted by University of Pennsylvania, Perelman School of Medicine’s
Center for Real-World Effectiveness and Safety of Therapeutics (CREST)

Virtual, via Zoom on June 9–12 and June 15–18, 2026 (8 consecutive business days for 3 hours/day plus a 15-minute break)

Individuals interested in target trial emulation and RWE, including students, researchers, clinicians, regulators, and industry professionals seeking to strengthen their understanding of topical epidemiologic methods.

Registration will open in February
Early Bird Registration rate ends on April 15th.

Prework: Enrollees will receive instructions for how to download and access R on a PC or Mac

University credit is not awarded, and transcripts are not provided.

Early Bird Rate (Sign up on or before April 15th):

After April 15th:

World Bank Registration is for residents of a lower-middle income or low-income country.
Learn more about World Bank classifications here

Contact Info:

General Inquiries/Questions: 
Charles Leonard celeonard@pennmedicine.upenn.edu

Registration Questions:
Adrianne Sanogo asanogo@pennmedicine.upenn.edu