Li Shen, PhD, FAIMBE, FACMI, FAMIA

Dr. Shen is a Professor and the Deputy Director of the Informatics Division in the Department of Biostatistics, Epidemiology and Informatics at the Perelman School of Medicine in the University of Pennsylvania. He holds secondary appointment in Department of Radiology, and graduate group appointments in AMCS, Bioengineering, GGEB, GCB, and Neuroscience. He is a Senior Fellow at the Institute for Biomedical Informatics (IBI) and the Leonard Davis Institute of Health Economics. He serves as Associate Director for Bioinformatics at the IBI, Faculty Director of the IBI Bioinformatics Core, and Co-Director of the AI2D Center.

Dr. Shen obtained his Ph.D. degree in Computer Science from Dartmouth College. His research spans machine learning, medical image computing, biomedical and health informatics, trustworthy AI, NLP/LLMs, network science, imaging genomics, and multi-omics and systems biology, with applications to Alzheimer’s disease and related dementias (ADRD) and other complex disorders. His primary focus is on developing and applying advanced AI strategies to analyze large-scale biobank and health datasets, with the goal of advancing the understanding, early detection, treatment, prevention, and overall healthcare of complex disorders. He also explores emerging frontiers such as generative AI, agentic AI, and trustworthy multimodal AI to push the boundaries of biomedical research.

Dr. Shen has served on a variety of scientific journal editorial boards, grant review committees, and organizing committees of professional meetings in medical image computing and biomedical informatics. He served as the Executive Director of the MICCAI Society (2016-2019). He is a fellow of the American Institute for Medical and Biological Engineering (AIMBE), the American College of Medical Informatics (ACMI) and the American Medical Informatics Association (AMIA), a distinguished member of the Association for Computing Machinery (ACM), and a distinguished contributor of the IEEE Computer Society.