John H. Holmes, PhD, FACE, FACMI, FIAHSI, FAMIA
Professor of Medical Informatics in Epidemiology
Open for Collaboration on:
Agent-based models in epidemiology, Foundation models in epidemiologic research, Injury epidemiology, Health disparities in urban populations
Open for Collaboration on:
Agent-based models in epidemiology, Foundation models in epidemiologic research, Injury epidemiology, Health disparities in urban populations
John H. Holmes, PhD, is Professor of Medical Informatics in Epidemiology at the University of Pennsylvania Perelman School of Medicine. He is the Associate Director for Education and Training and Interim Chair of the Penn Institute for Biomedical Informatics and is Past-Chair of the Doctoral Program in Epidemiology. He has mentored or co-mentored over 50 pre- and post-doctoral students in informatics or epidemiology, and has developed curricula for graduate training in epidemiology and biomedical informatics as well as short courses in these disciplines.
Dr. Holmes has been recognized nationally and internationally for his work on developing and applying new approaches to mining epidemiologic surveillance data, as well as his efforts at furthering educational initiatives in clinical research. Dr. Holmes’ research interests are focused on the intersection of medical informatics and epidemiologic research, specifically evolutionary computation and machine learning approaches to knowledge discovery in clinical databases, deep electronic phenotyping, interoperable information systems infrastructures for epidemiologic surveillance, and their application to a broad array of clinical domains. He has been deeply engaged in simulation through agent-based and network models of social, behavioral, and policy issues that affect health in the context of ever-changing environments.
Additional Appointments and Affiliations
- Senior Fellow, Leonard Davis Institute of Health Economics, Wharton School, University of Pennsylvania
- Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine
- Senior Scholar and Co-Director, Education and Trainng Core, Penn Injury Science Center, University of Pennsylvania
- Senior Fellow, Center for Public Health, School of Medicine University of Pennsylvania
- Associate Director for Education and Training and Interim Director, Institute for Biomedical Informatics, University of Pennsylvania Perelman School of Medicine
- Scholar, Center for Global Health, University of Pennsylvania Perelman School of Medicine
Graduate Group Affiliations
- Graduate Group in Epidemiology and Biostatistics
- Graduate Group in Genomics and Computational Biology
Awards and Honors
- Fellow, American College of Epidemiology (ACE)
- Fellow, American College of Medical Informatics (ACMI)
- Fellow, American Medical Informatics Association (AMIA)
- Inaugural Fellow, International Academy of Health Sciences Informatics (IAHSI)
- Fellow, College of Physicians of Philadelphia (CPP)
- Christian R. and Mary F. Lindback Award for Distinguished Teaching (2024)
Research Highlights
Dr. Holmes’ research interests are focused on the intersection of medical informatics and epidemiologic research, specifically evolutionary computation and machine learning approaches to knowledge discovery in clinical databases, deep electronic phenotyping, interoperable information systems infrastructures for epidemiologic surveillance, and their application to a broad array of clinical domains. Most recently, he has been deeply engaged in simulation through agent-based and network models of social, behavioral, and policy issues that affect health in the context of ever-changing environments, especially as these pertain to social determinants of health, with a particular interet in unitential injury in urban neighborhoods. He is the site Principal Investigator for the Mary Tyler Moore Vision Initiative Ocular Biorepository and Resource Center and for the Cardiovascular Biorepository for Type 1 Diabetes Program (CaRe-T1D).